Ontology highlight
ABSTRACT:
SUBMITTER: Mo J
PROVIDER: S-EPMC5386247 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Mo Jingxin J Eggers Paul K PK Chen Xianjue X Ahamed Muhammad Rizwan Hussain MR Becker Thomas T Yong Lim Lee L Raston Colin L CL
Scientific reports 20150522
Vesicles 107 ± 19 nm in diameter, based on the self-assembly of tetra-para-phosphonomethyl calix[4]- arene bearing n-hexyl moieties attached to the phenolic oxygen centres, are effective in binding carboplatin within the cavity of the macrocycle under shear induced within a dynamic thin film in a continuous flow vortex fluidic device. Post shearing the vesicles maintain similar diameters and retain carboplatin within the cavity of the calixarene in a hierarchical structure, with their size and m ...[more]