Increased expression of two multidrug transporter-like genes is associated with ethidium bromide and ciprofloxacin resistance in Mycoplasma hominis.
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ABSTRACT:
SUBMITTER: Raherison S
PROVIDER: S-EPMC538859 | biostudies-literature | 2005 Jan
REPOSITORIES: biostudies-literature
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Increased expression of two multidrug transporter-like genes is associated with ethidium bromide and ciprofloxacin resistance in Mycoplasma hominis.
Raherison S S Gonzalez P P Renaudin H H Charron A A Bébéar C C Bébéar C M CM
Antimicrobial agents and chemotherapy 20050101 1
Two genes, md1 and md2, coding for multidrug resistance ATP-binding cassette transporters were identified in Mycoplasma hominis PG21. Expression of these two genes, quantified by quantitative competitive reverse transcription-PCR, was significantly increased in ethidium bromide-resistant strains of M. hominis compared to that in M. hominis PG21. ...[more]
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