Circulating MiRNAs as biomarkers of gait speed responses to aerobic exercise training in obese older adults.
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ABSTRACT:
SUBMITTER: Zhang T
PROVIDER: S-EPMC5391238 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Publications
Circulating MiRNAs as biomarkers of gait speed responses to aerobic exercise training in obese older adults.
Zhang Tan T Brinkley Tina E TE Liu Keqin K Feng Xin X Marsh Anthony P AP Kritchevsky Stephen S Zhou Xiaobo X Nicklas Barbara J BJ
Aging 20170301 3
Gait speed is a useful predictor of adverse outcomes, including incident mobility disability and mortality in older adults. While aerobic exercise training (AEX) is generally an effective therapy to improve gait speed, individual responses are highly variable. Circulating microRNAs (miRNAs) may contribute to inter-individual changes in gait speed with AEX. We examined whether plasma miRNAs are associated with gait speed changes (dGaitSp) in 33 obese older adults (age: 69.3±3.6 years, BMI: 34.0±3 ...[more]
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