Ontology highlight
ABSTRACT:
SUBMITTER: Plasch K
PROVIDER: S-EPMC5396361 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Advanced synthesis & catalysis 20170118 6
In order to extend the applicability of the regioselective enzymatic carboxylation of phenols, the substrate scope of <i>o</i>-benzoic acid (de)carboxylases has been investigated towards complex molecules with an emphasis on flavouring agents and polyphenols possessing antioxidant properties. <i>o</i>-Hydroxycarboxylic acid products were obtained with perfect regioselectivity, in moderate to excellent yields. The applicability of this method was proven by the regioselective bio-carboxylation of ...[more]