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Regioselective enzymatic carboxylation of phenols and hydroxystyrene derivatives.

ABSTRACT: The enzymatic carboxylation of phenol and styrene derivatives using (de)carboxylases in carbonate buffer proceeded in a highly regioselective fashion: Benzoic acid (de)carboxylases selectively formed o-hydroxybenzoic acid derivatives, phenolic acid (de)carboxylases selectively acted at the ?-carbon atom of styrenes forming (E)-cinnamic acids.

SUBMITTER: Wuensch C

PROVIDER: S-EPMC3593611 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature

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Regioselective enzymatic carboxylation of phenols and hydroxystyrene derivatives.

Wuensch Christiane C Glueck Silvia M SM Gross Johannes J Koszelewski Dominik D Schober Markus M Faber Kurt K

Organic letters 20120403 8

The enzymatic carboxylation of phenol and styrene derivatives using (de)carboxylases in carbonate buffer proceeded in a highly regioselective fashion: Benzoic acid (de)carboxylases selectively formed o-hydroxybenzoic acid derivatives, phenolic acid (de)carboxylases selectively acted at the β-carbon atom of styrenes forming (E)-cinnamic acids. ...[more]

PMID: 22471935

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