Ontology highlight
ABSTRACT:
SUBMITTER: Marquardt D
PROVIDER: S-EPMC5397887 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Marquardt Drew D Heberle Frederick A FA Miti Tatiana T Eicher Barbara B London Erwin E Katsaras John J Pabst Georg G
Langmuir : the ACS journal of surfaces and colloids 20170203 15
We measured the transbilayer diffusion of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) in large unilamellar vesicles, in both the gel (L<sub>β'</sub>) and fluid (L<sub>α</sub>) phases. The choline resonance of headgroup-protiated DPPC exchanged into the outer leaflet of headgroup-deuterated DPPC-d13 vesicles was monitored using <sup>1</sup>H NMR spectroscopy, coupled with the addition of a paramagnetic shift reagent. This allowed us to distinguish between the inner and outer bilayer leafle ...[more]