Tumor Vaccines for Malignant Gliomas.
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ABSTRACT:
SUBMITTER: Srinivasan VM
PROVIDER: S-EPMC5398993 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Publications
Tumor Vaccines for Malignant Gliomas.
Srinivasan Visish M VM Ferguson Sherise D SD Lee Sungho S Weathers Shiao-Pei SP Kerrigan Brittany C Parker BCP Heimberger Amy B AB
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20170401 2
Despite continued research efforts, glioblastoma multiforme (GBM) remains the deadliest brain tumor. Immunotherapy offers a novel way to treat this disease, the genetic signature of which is not completely elucidated. Additionally, these tumors are known to induce immunosuppression in the surrounding tumor microenvironment via an array of mechanisms, making effective treatment all the more difficult. The immunotherapeutic strategy of using tumor vaccines offers a way to harness the activity of t ...[more]
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