Ontology highlight
ABSTRACT:
SUBMITTER: Patil NA
PROVIDER: S-EPMC5406294 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Patil Nitin A NA Rosengren K Johan KJ Separovic Frances F Wade John D JD Bathgate Ross A D RAD Hossain Mohammed Akhter MA
British journal of pharmacology 20170119 10
The human relaxin peptide family consists of seven cystine-rich peptides, four of which are known to signal through relaxin family peptide receptors, RXFP1-4. As these peptides play a vital role physiologically and in various diseases, they are of considerable importance for drug discovery and development. Detailed structure-activity relationship (SAR) studies towards understanding the role of important residues in each of these peptides have been reported over the years and utilized for the des ...[more]