Ontology highlight
ABSTRACT:
SUBMITTER: Haag C
PROVIDER: S-EPMC5415202 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Haag Carl C Pohlmann Thomas T Feldbrügge Michael M
PLoS genetics 20170419 4
In highly polarised cells, like fungal hyphae, early endosomes function in both endocytosis as well as long-distance transport of various cargo including mRNA and protein complexes. However, knowledge on the crosstalk between these seemingly different trafficking processes is scarce. Here, we demonstrate that the ESCRT regulator Did2 coordinates endosomal transport in fungal hyphae of Ustilago maydis. Loss of Did2 results in defective vacuolar targeting, less processive long-distance transport a ...[more]