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Kinesin Motor Enzymology: Chemistry, Structure, and Physics of Nanoscale Molecular Machines.


ABSTRACT: Molecular motors are enzymes that convert chemical potential energy into controlled kinetic energy for mechanical work inside cells. Understanding the biophysics of these motors is essential for appreciating life as well as apprehending diseases that arise from motor malfunction. This review focuses on kinesin motor enzymology with special emphasis on the literature that reports the chemistry, structure and physics of several different kinesin superfamily members.

SUBMITTER: Cochran JC 

PROVIDER: S-EPMC5418420 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature

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Kinesin Motor Enzymology: Chemistry, Structure, and Physics of Nanoscale Molecular Machines.

Cochran J C JC  

Biophysical reviews 20150213 3


Molecular motors are enzymes that convert chemical potential energy into controlled kinetic energy for mechanical work inside cells. Understanding the biophysics of these motors is essential for appreciating life as well as apprehending diseases that arise from motor malfunction. This review focuses on kinesin motor enzymology with special emphasis on the literature that reports the chemistry, structure and physics of several different kinesin superfamily members. ...[more]

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