Ontology highlight
ABSTRACT:
SUBMITTER: Theunissen C
PROVIDER: S-EPMC5418647 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Theunissen Cédric C Wang Jianjun J Evano Gwilherm G
Chemical science 20170320 5
An efficient and broadly applicable process is reported for the direct alkylation of C-H bonds in heteroarenes, privileged scaffolds in many areas of science. This reaction is based on the copper-catalyzed addition of alkyl radicals generated from activated secondary and tertiary alkyl bromides to a wide range of arenes, including furans, thiophenes, pyrroles, and their benzo-fused derivatives, as well as coumarins and quinolinones. ...[more]