Ontology highlight
ABSTRACT:
SUBMITTER: Bryant DM
PROVIDER: S-EPMC5419050 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Bryant Donald M DM Johnson Kimberly K DiTommaso Tia T Tickle Timothy T Couger Matthew Brian MB Payzin-Dogru Duygu D Lee Tae J TJ Leigh Nicholas D ND Kuo Tzu-Hsing TH Davis Francis G FG Bateman Joel J Bryant Sevara S Guzikowski Anna R AR Tsai Stephanie L SL Coyne Steven S Ye William W WW Freeman Robert M RM Peshkin Leonid L Tabin Clifford J CJ Regev Aviv A Haas Brian J BJ Whited Jessica L JL
Cell reports 20170101 3
Mammals have extremely limited regenerative capabilities; however, axolotls are profoundly regenerative and can replace entire limbs. The mechanisms underlying limb regeneration remain poorly understood, partly because the enormous and incompletely sequenced genomes of axolotls have hindered the study of genes facilitating regeneration. We assembled and annotated a de novo transcriptome using RNA-sequencing profiles for a broad spectrum of tissues that is estimated to have near-complete sequence ...[more]