Ontology highlight
ABSTRACT:
SUBMITTER: Sarangi BR
PROVIDER: S-EPMC5423523 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Sarangi Bibhu Ranjan BR Gupta Mukund M Doss Bryant L BL Tissot Nicolas N Lam France F Mège René-Marc RM Borghi Nicolas N Ladoux Benoît B
Nano letters 20161223 1
Focal adhesions (FAs) are important mediators of cell-substrate interactions. One of their key functions is the transmission of forces between the intracellular acto-myosin network and the substrate. However, the relationships between cell traction forces, FA architecture, and molecular forces within FAs are poorly understood. Here, by combining Förster resonance energy transfer (FRET)-based molecular force biosensors with micropillar-based traction force sensors and high-resolution fluorescence ...[more]