Ontology highlight
ABSTRACT:
SUBMITTER: Kocgozlu L
PROVIDER: S-EPMC5423527 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Kocgozlu Leyla L Saw Thuan Beng TB Le Anh Phuong AP Yow Ivan I Shagirov Murat M Wong Eunice E Mège René-Marc RM Lim Chwee Teck CT Toyama Yusuke Y Ladoux Benoit B
Current biology : CB 20161013 21
The control of tissue growth, which is a key to maintain the protective barrier function of the epithelium, depends on the balance between cell division and cell extrusion rates [1, 2]. Cells within confluent epithelial layers undergo cell extrusion, which relies on cell-cell interactions [3] and actomyosin contractility [4, 5]. Although it has been reported that cell extrusion is also dependent on cell density [6, 7], the contribution of tissue mechanics, which is tightly regulated by cell dens ...[more]