Ontology highlight
ABSTRACT:
SUBMITTER: Durkin CH
PROVIDER: S-EPMC5425256 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Durkin Charlotte H CH Leite Flavia F Cordeiro João V JV Handa Yutaka Y Arakawa Yoshiki Y Valderrama Ferran F Way Michael M
Developmental cell 20170501 3
RhoA-mediated regulation of myosin-II activity in the actin cortex controls the ability of cells to contract and bleb during a variety of cellular processes, including cell migration and division. Cell contraction and blebbing also frequently occur as part of the cytopathic effect seen during many different viral infections. We now demonstrate that the vaccinia virus protein F11, which localizes to the plasma membrane, is required for ROCK-mediated cell contraction from 2 hr post infection. Curi ...[more]