Ontology highlight
ABSTRACT:
SUBMITTER: Kamina AD
PROVIDER: S-EPMC5436847 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
PloS one 20170518 5
RNA binding proteins are involved in many aspects of RNA metabolism. In Trypanosoma brucei, our laboratory has identified two trypanosome-specific RNA binding proteins P34 and P37 that are involved in the maturation of the 60S subunit during ribosome biogenesis. These proteins are part of the T. brucei 5S ribonucleoprotein particle (5S RNP) and P34 binds to 5S ribosomal RNA (rRNA) and ribosomal protein L5 through its N-terminus and its RNA recognition motif (RRM) domains. We generated truncated ...[more]