Ontology highlight
ABSTRACT:
SUBMITTER: Warszycki D
PROVIDER: S-EPMC5438429 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Warszycki Dawid D Śmieja Marek M Kafel Rafał R
Molecular diversity 20170209 2
The Average Information Content Maximization algorithm (AIC-MAX) based on mutual information maximization was recently introduced to select the most discriminatory features. Here, this methodology was applied to select the most significant bits from the Klekota-Roth fingerprint for serotonin receptors ligands as well as to select the most important features for distinguishing ligands with activity for one receptor versus another. The interpretation of selected bits and machine-learning experimen ...[more]