Ontology highlight
ABSTRACT:
SUBMITTER: Yasgar A
PROVIDER: S-EPMC5444910 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Yasgar Adam A Jadhav Ajit A Simeonov Anton A Coussens Nathan P NP
Methods in molecular biology (Clifton, N.J.) 20160101
AlphaScreen technology has been routinely utilized in high-throughput screening assays to quantify analyte accumulation or depletion, bimolecular interactions, and post-translational modifications. The high signal-to-background, dynamic range, and sensitivity associated with AlphaScreens as well as the homogenous assay format and reagent stability make the technology particularly well suited for high-throughput screening applications. Here, we describe the development of AlphaScreen assays to id ...[more]