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Anemia in critical illness: insights into etiology, consequences, and management.


ABSTRACT: Anemia is common in the intensive care unit, and may be associated with adverse consequences. However, current options for correcting anemia are not without problems and presently lack convincing efficacy for improving survival in critically ill patients. In this article we review normal red blood cell physiology; etiologies of anemia in the intensive care unit; its association with adverse outcomes; and the risks, benefits, and efficacy of various management strategies, including blood transfusion, erythropoietin, blood substitutes, iron therapy, and minimization of diagnostic phlebotomy.

SUBMITTER: Hayden SJ 

PROVIDER: S-EPMC5448578 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature

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Anemia in critical illness: insights into etiology, consequences, and management.

Hayden Shailaja J SJ   Albert Tyler J TJ   Watkins Timothy R TR   Swenson Erik R ER  

American journal of respiratory and critical care medicine 20120126 10


Anemia is common in the intensive care unit, and may be associated with adverse consequences. However, current options for correcting anemia are not without problems and presently lack convincing efficacy for improving survival in critically ill patients. In this article we review normal red blood cell physiology; etiologies of anemia in the intensive care unit; its association with adverse outcomes; and the risks, benefits, and efficacy of various management strategies, including blood transfus  ...[more]

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