Ontology highlight
ABSTRACT:
SUBMITTER: Eritano AS
PROVIDER: S-EPMC5449151 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Eritano Anthony S AS Altamirano Arturo A Beyeler Sarah S Gaytan Norma N Velasquez Mark M Riggs Blake B
Molecular biology of the cell 20170405 11
Asymmetric cell division is the primary mechanism to generate cellular diversity, and it relies on the correct partitioning of cell fate determinants. However, the mechanism by which these determinants are delivered and positioned is poorly understood, and the upstream signal to initiate asymmetric cell division is unknown. Here we report that the endoplasmic reticulum (ER) is asymmetrically partitioned during mitosis in epithelial cells just before delamination and selection of a proneural cell ...[more]