Ontology highlight
ABSTRACT:
SUBMITTER: Haaker J
PROVIDER: S-EPMC5458514 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Nature communications 20170525
Many fearful expectations are shaped by observation of aversive outcomes to others. Yet, the neurochemistry regulating social learning is unknown. Previous research has shown that during direct (Pavlovian) threat learning, information about personally experienced outcomes is regulated by the release of endogenous opioids, and activity within the amygdala and periaqueductal gray (PAG). Here we report that blockade of this opioidergic circuit enhances social threat learning through observation in ...[more]