Ontology highlight
ABSTRACT:
SUBMITTER: Baharom F
PROVIDER: S-EPMC5462357 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Baharom Faezzah F Thomas Oliver S OS Lepzien Rico R Mellman Ira I Chalouni Cécile C Smed-Sörensen Anna A
PloS one 20170607 6
Influenza A viruses (IAV) primarily target respiratory epithelial cells, but can also replicate in immune cells, including human dendritic cells (DCs). Super-resolution microscopy provides a novel method of visualizing viral trafficking by overcoming the resolution limit imposed by conventional light microscopy, without the laborious sample preparation of electron microscopy. Using three-color Stimulated Emission Depletion (STED) microscopy, we visualized input IAV nucleoprotein (NP), early and ...[more]