Ontology highlight
ABSTRACT:
SUBMITTER: Budiu RA
PROVIDER: S-EPMC5464739 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Budiu Raluca A RA Vlad Anda M AM Nazario Linda L Bathula Chandra C Cooper Kristine L KL Edmed Jessica J Thaker Premal H PH Urban Julie J Kalinski Pawel P Lee Adrian V AV Elishaev Esther L EL Conrads Thomas P TP Flint Melanie S MS
Cancer and clinical oncology 20161111 1
The ability of stress to induce immune suppression is widely recognized, but the mechanisms underlying the effects of stress on the adaptive immune system during tumor progression are not completely understood. To study the effect of stress on the immune system <i>in vivo</i>, we used a preclinical immunocompetent mouse model bearing 4T1 mammary adenocarcinoma cells. Mice were randomized into 4 groups, including social isolation (SI), acute restraint stress (aRRS), chronic restraint stress (cRRS ...[more]