Should eculizumab be discontinued in patients with atypical hemolytic uremic syndrome?
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SUBMITTER: Rodriguez E
PROVIDER: S-EPMC5466109 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
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Should eculizumab be discontinued in patients with atypical hemolytic uremic syndrome?
Rodriguez Eva E Barrios Clara C Soler Maria José MJ
Clinical kidney journal 20170420 3
Atypical hemolytic uremic syndrome (aHUS) is a life-threatening disorder for which prompt diagnosis and eculizumab treatment is indicated. The time for relapse and patients at risk for relapse after eculizumab discontinuation are unknown. While some authors believe there is no clinical evidence supporting eculizumab discontinuation, which may be associated with high collateral risks such as loss of renal function, other authors believe that the drug can be safely discontinued with close patient ...[more]
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