Ontology highlight
ABSTRACT:
SUBMITTER: Trimarchi H
PROVIDER: S-EPMC7543344 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Trimarchi Hernán H Gianserra Raquel R Lampo Mauro M Monkowski Matias M Lodolo Jimena J
Clinical kidney journal 20200927 5
Atypical hemolytic uremic syndrome (aHUS) treatment consists of eculizumab. Severe acute respiratory syndrome coronavirus 2 causes severe pneumonia and endothelial injury that leads to a prothrombotic state that may be complicated by macrovascular and microvascular thrombosis. Complement activation is thought to contribute to endothelial injury and there are at least seven ongoing clinical trials testing six different anti-complement strategies for coronavirus disease 2019 (COVID-19), including ...[more]