Ontology highlight
ABSTRACT:
SUBMITTER: Lal S
PROVIDER: S-EPMC5466444 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Lal Shruti S Cheung Edwin C EC Zarei Mahsa M Preet Ranjan R Chand Saswati N SN Mambelli-Lisboa Nicole C NC Romeo Carmella C Stout Matthew C MC Londin Eric E Goetz Austin A Lowder Cinthya Y CY Nevler Avinoam A Yeo Charles J CJ Campbell Paul M PM Winter Jordan M JM Dixon Dan A DA Brody Jonathan R JR
Molecular cancer research : MCR 20170227 6
Pancreatic ductal adenocarcinoma (PDA) is the third leading cause of cancer-related deaths in the United States, whereas colorectal cancer is the third most common cancer. The RNA-binding protein HuR (ELAVL1) supports a pro-oncogenic network in gastrointestinal (GI) cancer cells through enhanced HuR expression. Using a publically available database, HuR expression levels were determined to be increased in primary PDA and colorectal cancer tumor cohorts as compared with normal pancreas and colon ...[more]