Ontology highlight
ABSTRACT:
SUBMITTER: Shen TC
PROVIDER: S-EPMC5466618 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Scientific reports 20170609 1
Asthma is an inflammatory disease and interleukin 12 (IL-12) may play a regulatory role in allergen-induced inflammation. The aim of this study was to investigate the association of polymorphisms in IL-12A/IL-12B with asthma. The asthma group included 198 adult patients and the control group included 453 individuals without asthma that were frequency-matched by gender and age. The distribution of genotypic and allelic frequencies of IL-12A rs568408 demonstrated significant differences between ca ...[more]