Ontology highlight
ABSTRACT:
SUBMITTER: Li F
PROVIDER: S-EPMC5505239 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
ACS infectious diseases 20160922 10
Despite the existence of flu vaccines and small-molecule antiviral drugs, influenza virus infection remains a public health concern that warrants immediate attention. As resistance to the only orally bioavailable drug, oseltamivir, has been continuously reported, there is a clear need to develop the next-generation of anti-influenza drugs. We chose the influenza A virus M2-S31N mutant proton channel as the drug target to address this need as it is one of the most conserved viral proteins and per ...[more]