Ontology highlight
ABSTRACT:
SUBMITTER: Rissanen I
PROVIDER: S-EPMC5510225 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Rissanen Ilona I Ahmed Asim A AA Azarm Kristopher K Beaty Shannon S Hong Patrick P Nambulli Sham S Duprex W Paul WP Lee Benhur B Bowden Thomas A TA
Nature communications 20170712
In 2012, cases of lethal pneumonia among Chinese miners prompted the isolation of a rat-borne henipavirus (HNV), Mòjiāng virus (MojV). Although MojV is genetically related to highly pathogenic bat-borne henipaviruses, the absence of a conserved ephrin receptor-binding motif in the MojV attachment glycoprotein (MojV-G) indicates a differing host-cell recognition mechanism. Here we find that MojV-G displays a six-bladed β-propeller fold bearing limited similarity to known paramyxoviral attachment ...[more]