Ontology highlight
ABSTRACT:
SUBMITTER: Chouchane M
PROVIDER: S-EPMC5511102 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Chouchane Malek M Melo de Farias Ana Raquel AR Moura Daniela Maria de Sousa DMS Hilscher Markus Michael MM Schroeder Timm T Leão Richardson Naves RN Costa Marcos Romualdo MR
Stem cell reports 20170608 1
Astroglial cells isolated from the rodent postnatal cerebral cortex are particularly susceptible to lineage reprogramming into neurons. However, it remains unknown whether other astroglial populations retain the same potential. Likewise, little is known about the fate of induced neurons (iNs) in vivo. In this study we addressed these questions using two different astroglial populations isolated from the postnatal brain reprogrammed either with Neurogenin-2 (Neurog2) or Achaete scute homolog-1 (A ...[more]