Unknown

Dataset Information

0

Ligand-Promoted meta-C-H Functionalization of Benzylamines.

ABSTRACT: Meta-C-H functionalization of benzylamines has been developed using a PdII /transient mediator strategy. Using 2-pyridone ligands and 2-carbomethoxynorbornene (NBE-CO2 Me) as the mediator, arylation, amination, and chlorination of benzylamines are realized. This protocol features a broad substrate scope and is compatible with heterocylic coupling partners. Moreover, the loading of the Pd can be lowered to 2.5?mol?% by using the optimal ligand.

SUBMITTER: Wang P 

PROVIDER: S-EPMC5512280 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Ligand-Promoted meta-C-H Functionalization of Benzylamines.

Wang Peng P   Farmer Marcus E ME   Yu Jin-Quan JQ  

Angewandte Chemie (International ed. in English) 20170330 18

Meta-C-H functionalization of benzylamines has been developed using a Pd<sup>II</sup> /transient mediator strategy. Using 2-pyridone ligands and 2-carbomethoxynorbornene (NBE-CO<sub>2</sub> Me) as the mediator, arylation, amination, and chlorination of benzylamines are realized. This protocol features a broad substrate scope and is compatible with heterocylic coupling partners. Moreover, the loading of the Pd can be lowered to 2.5 mol % by using the optimal ligand. ...[more]

Similar Datasets

Unknown S,O-Ligand-Promoted Palladium-Catalyzed C-H Functionalization Reactions of Nondirected Arenes.
| S-EPMC5617328 | biostudies-literature
Unknown Ligand-Promoted meta-C-H Amination and Alkynylation.
| S-EPMC5513786 | biostudies-literature
Unknown Ligand-Enabled meta-Selective C-H Arylation of Nosyl-Protected Phenethylamines, Benzylamines, and 2-Aryl Anilines.
| S-EPMC5497681 | biostudies-other
Unknown Ligand Promoted meta-C-H Chlorination of Anilines and Phenols.
| S-EPMC5512287 | biostudies-literature
Unknown Ligand-Promoted Meta-C-H Arylation of Anilines, Phenols, and Heterocycles.
| S-EPMC5512281 | biostudies-literature
Unknown Multi-Functionalization of Polymers by Strain-Promoted Cycloadditions.
| S-EPMC3916133 | biostudies-literature
Unknown DABCO-promoted photocatalytic C-H functionalization of aldehydes.
| S-EPMC8712972 | biostudies-literature
Unknown Computational Study of Rh-Catalyzed Carboacylation of Olefins: Ligand-Promoted Rhodacycle Isomerization Enables Regioselective C-C Bond Functionalization of Benzocyclobutenones.
| S-EPMC4878673 | biostudies-literature
Unknown Metal-Free Oxidative Coupling of Benzylamines to Imines under an Oxygen Atmosphere Promoted Using Salicylic Acid Derivatives as Organocatalysts.
| S-EPMC6640803 | biostudies-literature
Unknown Acetic Acid Promoted Redox Annulations with Dual C-H Functionalization.
| S-EPMC5460294 | biostudies-literature