Ontology highlight
ABSTRACT:
SUBMITTER: Bimber BN
PROVIDER: S-EPMC5513488 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Bimber Benjamin N BN Ramakrishnan Ranjani R Cervera-Juanes Rita R Madhira Ravi R Peterson Samuel M SM Norgren Robert B RB Ferguson Betsy B
Genomics 20170423 3-4
Rhesus macaques are an important pre-clinical model of human disease. To advance our understanding of genomic variation that may influence disease, we surveyed genome-wide variation in 21 rhesus macaques. We employed best-practice variant calling, validated with Mendelian inheritance. Next, we used alignment data from our cohort to detect genomic regions likely to produce inaccurate genotypes, potentially due to either gene duplication or structural variation between individuals. We generated a ...[more]