Ontology highlight
ABSTRACT:
SUBMITTER: Talboom JS
PROVIDER: S-EPMC5514987 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Talboom Joshua S JS Velazquez Ramon R Oddo Salvatore S
NPJ aging and mechanisms of disease 20151015
Age-dependent cognitive decline is a major debilitating event affecting even individuals who are otherwise healthy. Understanding the molecular basis underlying these changes may increase the healthspan of the elderly population. It may also reveal insights into the pathogenesis of numerous neurodegenerative disorders characterized by cognitive deficits, as aging is the major risk factor for most of these disorders. Alzheimer's disease (AD), the most common neurodegenerative disorder, first mani ...[more]