Integrated expression analysis identifies transcription networks in mouse and human gastric neoplasia.
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ABSTRACT:
SUBMITTER: Chen Z
PROVIDER: S-EPMC5524517 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Publications
Integrated expression analysis identifies transcription networks in mouse and human gastric neoplasia.
Chen Zheng Z Soutto Mohammed M Rahman Bushra B Fazili Muhammad W MW Peng DunFa D Blanca Piazuelo Maria M Chen Heidi H Kay Washington M M Shyr Yu Y El-Rifai Wael W
Genes, chromosomes & cancer 20170404 7
Gastric cancer (GC) is a leading cause of cancer-related deaths worldwide. The Tff1 knockout (KO) mouse model develops gastric lesions that include low-grade dysplasia (LGD), high-grade dysplasia (HGD), and adenocarcinomas. In this study, we used Affymetrix microarrays gene expression platforms for analysis of molecular signatures in the mouse stomach [Tff1-KO (LGD) and Tff1 wild-type (normal)] and human gastric cancer tissues and their adjacent normal tissue samples. Combined integrated bioinfo ...[more]
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