Ontology highlight
ABSTRACT:
SUBMITTER: Akmammedov A
PROVIDER: S-EPMC5537222 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Akmammedov Arslan A Geigges Marco M Paro Renato R
Scientific reports 20170731 1
An ideal transgenic gene expression system is inducible, non-leaky, and well tolerated by the target organism. While the former has been satisfactorily realized, leakiness and heavy physiological burden imposed by the existing systems are still prominent hurdles in their successful implementation. Here we describe a new system for non-leaky expression of transgenes in Drosophila. PRExpress is based on a single transgenic construct built from endogenous components, the inducible hsp70 promoter an ...[more]