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Photoswitchable particles for on-demand degradation and triggered release.

ABSTRACT: On-demand degradable polymer particles are fabricated via electrospraying of a solution of acetal-protected dextran that further includes 2-(4-methoxystyryl)-4,6-bis(trichloromethyl)-1,3,5-triazine as a photoacid generator. The illumination of UV light gives rise to photoacid and activates the catalytic deprotection of hydroxyl groups of dextran, leading to controlled dissolution of the microparticles in water.

SUBMITTER: Park TH

PROVIDER: S-EPMC5550892 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature

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Photoswitchable particles for on-demand degradation and triggered release.

Park Tae-Hong TH Eyster Thomas W TW Lumley Joshua M JM Hwang Sangyeul S Lee Kyung Jin KJ Misra Asish A Rahmani Sahar S Lahann Joerg J

Small (Weinheim an der Bergstrasse, Germany) 20130419 18

On-demand degradable polymer particles are fabricated via electrospraying of a solution of acetal-protected dextran that further includes 2-(4-methoxystyryl)-4,6-bis(trichloromethyl)-1,3,5-triazine as a photoacid generator. The illumination of UV light gives rise to photoacid and activates the catalytic deprotection of hydroxyl groups of dextran, leading to controlled dissolution of the microparticles in water. ...[more]

PMID: 23606461

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