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Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016.


ABSTRACT: A novel mcr colistin resistance gene was identified in a strain of Salmonella enterica, monophasic variant of serovar Typhimurium (4,5,12:i:-?), isolated from a pig at slaughter in Italy in 2013, and in Escherichia coli strains collected during routine diagnostic of post-weaning diarrhoea in pigs from Spain and Belgium in 2015 and 2016. Immediate implementation of mcr-screening including this novel gene variant is required for Salmonella and E. coli from humans and food-producing animals in Europe.

SUBMITTER: Carattoli A 

PROVIDER: S-EPMC5553062 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature

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Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016.

Carattoli Alessandra A   Villa Laura L   Feudi Claudia C   Curcio Ludovica L   Orsini Serenella S   Luppi Andrea A   Pezzotti Giovanni G   Magistrali Chiara Francesca CF  

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20170801 31


A novel mcr colistin resistance gene was identified in a strain of Salmonella enterica, monophasic variant of serovar Typhimurium (4,5,12:i:- ), isolated from a pig at slaughter in Italy in 2013, and in Escherichia coli strains collected during routine diagnostic of post-weaning diarrhoea in pigs from Spain and Belgium in 2015 and 2016. Immediate implementation of mcr-screening including this novel gene variant is required for Salmonella and E. coli from humans and food-producing animals in Euro  ...[more]

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