Ontology highlight
ABSTRACT:
SUBMITTER: Perez-Riba A
PROVIDER: S-EPMC5567296 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Perez-Riba Albert A Itzhaki Laura S LS
Scientific reports 20170822 1
Quantitative determination of protein thermodynamic stability is fundamental to many research areas, both basic and applied. Although chemical-induced denaturation is the gold-standard method, it has been replaced in many settings by semi-quantitative approaches such as thermal stability measurements. The reason for this shift is that chemical denaturation experiments are labour-intensive, sample-costly and time-consuming, and it has been assumed that miniaturisation to a high-throughput format ...[more]