Screening of genetic variants in ADCYAP1R1, MME and 14q21 in a Swedish cluster headache cohort.
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ABSTRACT:
SUBMITTER: Ran C
PROVIDER: S-EPMC5567453 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
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Screening of genetic variants in ADCYAP1R1, MME and 14q21 in a Swedish cluster headache cohort.
Ran Caroline C Fourier Carmen C Michalska Julia M JM Steinberg Anna A Sjöstrand Christina C Waldenlind Elisabet E Belin Andrea Carmine AC
The journal of headache and pain 20170822 1
<h4>Background</h4>We have genotyped a Swedish cluster headache case-control population for three genetic variants representing the most significant markers identified in a recently published genome wide association study on cluster headache. The genetic variants were two common polymorphisms; rs12668955 in ADCYAP1R1 (adenylate cyclase activating polypeptide 1 receptor type 1), rs1006417, an intergenic variant on chromosome 14q21 and one rare mutation, rs147564881, in MME (membrane metalloendope ...[more]
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