Ontology highlight
ABSTRACT:
SUBMITTER: Kim KH
PROVIDER: S-EPMC5579509 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Kim Kyu-Han KH Lee Tae Ryong TR Cho Eun-Gyung EG
Experimental & molecular medicine 20170818 8
Our previous work has identified miR-125b as a negative regulator of melanogenesis. However, the specific melanogenesis-related genes targeted by this miRNA had not been identified. In this study, we established a screening strategy involving three consecutive analytical approaches-analysis of target genes of miR-125b, expression correlation analysis between each target gene and representative pigmentary genes, and functional analysis of candidate genes related to melanogenesis-to discover melan ...[more]