Ontology highlight
ABSTRACT:
SUBMITTER: Carson RH
PROVIDER: S-EPMC5580901 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Carson Richard H RH Lewis Charlotte R CR Erickson Mercede N MN Zagieboylo Anna P AP Naylor Bradley C BC Li Kelvin W KW Farnsworth Paul B PB Price John C JC
Journal of lipid research 20170725 9
Compartmentalization of metabolism into specific regions of the cell, tissue, and organ is critical to life for all organisms. Mass spectrometric imaging techniques have been valuable in identifying and quantifying concentrations of metabolites in specific locations of cells and tissues, but a true understanding of metabolism requires measurement of metabolite flux on a spatially resolved basis. Here, we utilize desorption ESI-MS (DESI-MS) to measure lipid turnover in the brains of mice. We show ...[more]