Ontology highlight
ABSTRACT:
SUBMITTER: Britvin SN
PROVIDER: S-EPMC5588587 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Acta crystallographica. Section E, Crystallographic communications 20170830 Pt 9
7-Aza-bicyclo-[2.2.1]heptane (7-aza-norbornane) is a bridged heterocyclic nucleus found in epibatidine, the alkaloid isolated from the skin of the tropical poison frog <i>Epipedobates tricolor</i>. Since epibatidine is known as one of the most potent acetyl-choline nicotinic receptor agonists, a plethora of literature has been devoted to this alkaloid. However, there are no structural data on the unsubstituted 7-aza-norbornane, the parent bicyclic ring of epibatidine and its derivatives. We here ...[more]