Ontology highlight
ABSTRACT:
SUBMITTER: Xiao X
PROVIDER: S-EPMC5590790 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Xiao Xiong X Liu Hui-Xia HX Shen Kuo K Cao Wei W Li Xiao-Qiang XQ
Biomolecules & therapeutics 20170901 5
The canonical transient receptor potential channels (TRPCs) constitute a series of nonselective cation channels with variable degrees of Ca<sup>2+</sup> selectivity. TRPCs consist of seven mammalian members, TRPC1, TRPC2, TRPC3, TRPC4, TRPC5, TRPC6, and TRPC7, which are further divided into four subtypes, TRPC1, TRPC2, TRPC4/5, and TRPC3/6/7. These channels take charge of various essential cell functions such as contraction, relaxation, proliferation, and dysfunction. This review, organized into ...[more]