Ontology highlight
ABSTRACT:
SUBMITTER: Tosi A
PROVIDER: S-EPMC5593712 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Tosi Anna A Dalla Santa Silvia S Cappuzzello Elisa E Marotta Carolina C Walerych Dawid D Del Sal Giannino G Zanovello Paola P Sommaggio Roberta R Rosato Antonio A
Oncoimmunology 20170405 8
The identification of universal tumor-specific antigens shared between multiple patients and/or multiple tumors is of great importance to overcome the practical limitations of personalized cancer immunotherapy. Recent studies support the involvement of DEPDC1 in many aspects of cancer traits, such as cell proliferation, resistance to induction of apoptosis and cell invasion, suggesting that it may play key roles in the oncogenic process. In this study, we report that DEPDC1 expression is upregul ...[more]