Ontology highlight
ABSTRACT:
SUBMITTER: Zeineddine A
PROVIDER: S-EPMC5603523 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Nature communications 20170918 1
The reluctance of gold to achieve oxidative addition reaction is considered as an intrinsic limitation for the development of gold-catalyzed cross-coupling reactions with simple and ubiquitous aryl halide electrophiles. Here, we report the rational construction of a Au(I)/Au(III) catalytic cycle involving a sequence of Csp<sup>2</sup>-X oxidative addition, Csp<sup>2</sup>-H auration and reductive elimination, allowing a gold-catalyzed direct arylation of arenes with aryl halides. Key to this dis ...[more]