Effect of localized hypoxia on Drosophila embryo development.
Ontology highlight
ABSTRACT:
SUBMITTER: Wang Z
PROVIDER: S-EPMC5608372 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Effect of localized hypoxia on Drosophila embryo development.
Wang Zhinan Z Oppegard Shawn C SC Eddington David T DT Cheng Jun J
PloS one 20170921 9
Environmental stress, such as oxygen deprivation, affects various cellular activities and developmental processes. In this study, we directly investigated Drosophila embryo development in vivo while cultured on a microfluidic device, which imposed an oxygen gradient on the developing embryos. The designed microfluidic device enabled both temporal and spatial control of the local oxygen gradient applied to the live embryos. Time-lapse live cell imaging was used to monitor the morphology and cellu ...[more]
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