Comparison of classical multi-locus sequence typing software for next-generation sequencing data.
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SUBMITTER: Page AJ
PROVIDER: S-EPMC5610716 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
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Comparison of classical multi-locus sequence typing software for next-generation sequencing data.
Page Andrew J AJ Alikhan Nabil-Fareed NF Carleton Heather A HA Seemann Torsten T Keane Jacqueline A JA Katz Lee S LS
Microbial genomics 20170704 8
Multi-locus sequence typing (MLST) is a widely used method for categorizing bacteria. Increasingly, MLST is being performed using next-generation sequencing (NGS) data by reference laboratories and for clinical diagnostics. Many software applications have been developed to calculate sequence types from NGS data; however, there has been no comprehensive review to date on these methods. We have compared eight of these applications against real and simulated data, and present results on: (1) the ac ...[more]
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