Ontology highlight
ABSTRACT:
SUBMITTER: Iwata T
PROVIDER: S-EPMC5638857 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Iwata Tetsuo T Niimura Yoshihito Y Kobayashi Chizuru C Shirakawa Daichi D Suzuki Hikoyu H Enomoto Takayuki T Touhara Kazushige K Yoshihara Yoshihiro Y Hirota Junji J
Nature communications 20171012 1
Individual olfactory sensory neurons express a single odorant receptor gene from either class I genes residing in a single cluster on a single chromosome or class II genes spread over multiple clusters on multiple chromosomes. Here, we identify an enhancer element for mouse class I genes, the J element, that is conserved through mammalian species from the platypus to humans. The J element regulates most class I genes expression by exerting an effect over ~ 3 megabases within the whole cluster. D ...[more]