Ontology highlight
ABSTRACT:
SUBMITTER: Wong JH
PROVIDER: S-EPMC5643532 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Scientific reports 20171016 1
Helicobacter pylori has been identified as one of the major causes of chronic gastritis, gastric and duodenal ulcers, and gastric cancer. Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria, and H. pylori LPS might play an exclusively important role in activating inflammatory pathways in monocytes and macrophages. To study the role of LPS in the underlying mechanism of inflammatory responses, we established an in vitro model using the human AGS gastric c ...[more]