Ontology highlight
ABSTRACT:
SUBMITTER: Roy A
PROVIDER: S-EPMC5649623 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Organic letters 20160229 6
Chiral ammonium salts were used to catalyze the isomerization of organomanganese-complexed alkynyl aldehydes to chiral allenal building blocks in moderate to good enantiomeric excesses. Normally, conjugated alkynyl aldehydes do not isomerize to their thermodynamically less stable allene isomers. However, with a manganese auxiliary in place to promote allene formation, asymmetric protonation of cumulenolate intermediates was realized using a variety of cinchonidinium salts in a weakly basic bipha ...[more]